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酪氨酸激酶抗体说明书

更新时间:2012-05-31 浏览次数:2424

 

 
 Goat Anti-SYK
Catalog Number :HZ99742 Quantity size : 0.1ml (dilute with pH 7.4
0.01 M PBS or antibody diluent ) Background:Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Specifically, calcium ions travel through either a phosphoinositide 3-kinase (PI 3-kinase)-dependent pathway when Syk is not phosphorylated, or through a phospholipase C (PLC) ©-dependent pathway when human Syk is phohsphorylated on Tyr 348 and Tyr 352. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events
 
pecificity :
              Anti-SYKis a goat polyclonal antibody unconjugated .
              specific for SYKof human, mouse, rat and rabbit
              use for western blotting,elisa,immunoprecipitation and immunohistochemistry
              Protein G affinity chromatography purification, purity :>95%
              Isotype: IgG
 
Application :
              Western blotting 1:100-500
              Immunohistochemistry 1:100-500
              ELISA 1:500-1000
              Optimal working dilutions must be determined by the end user. Storage: Store at -20for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

人脾脏酪氨酸激酶(Syk)ELISA Kit        48次  1200元,96次  2200元

 

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海劲马实验设备有限公司是一家专注于生命科海劲马实验设备有限公司是一家专注于生命科学和生物技术领域的企业。从事生物技术领域相关产品的开发,销售和技术服务。我们的主营业务为:ELISA试剂盒,化学试剂,标准品,抗体以及耗材。

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