马脾铁蛋白/铁蛋白（马脾）/ Ferritin from horse spleen/HSF

 Description
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Biochem/physiol Actions A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve （particularly in spleen, liver, intestinal mucosa, and bone marrow） and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
General description A shell of 24 protein subunits （apoferritin） and a core of Fe3+ ions with a peptide MW of 440 kDa.

Properties
sterility sterile-filtered
type Type I
form saline solution
mol wt H subunit mol wt ~21 kDa
  L subunit mol wt ~19 kDa
color red to brown
cation traces Cd: ≤1% （as % of ferritin）
storage temp. 2-8°C

Safety
WGK Germany NWG

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