人重组胰岛素/Insulin Human recombinant

 Description
Biochem/physiol Actions Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Properties
recombinant expressed in Escherichia coli
form powder
potency ≥27.5 USP units per mg （dry basis）
solubility 10 mM HCl: 20 mg/mL
suitability cell culture tested
Gene Information human ... INS（3630）
storage temp. −20°C

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany NWG
RTECS NM8900250

References
reference Smith, L.F., Species variation in the amino acid sequence of insulin. Am. J. Med. 40, 662-666, （1966）
  Kono, T., Insulin-sensitive glucose transport. Vitam. Horm. 7, 103-154, （1988）
  Morihara, K., et al., Semi-synthesis of human insulin by trypsin-catalysed replacement of Ala-B30 by Thr in porcine insulin. Nature 280, 412-413, （1979）

 Printable Reviews
Product ReviewsReview This Product
  
  
       

• D0069纤粘连蛋白/纤连蛋白（人血）/纤链蛋白/CIG/Fibronectin
• D0068琼脂糖凝胶4B蛋白A/Protein A-Sepharose 4B, Fast Flow from
• D0067肌红蛋白/Myoglobin from equine skeletal muscle
• D0066金属硫蛋白/Metallothionein/MT
• D0065琼脂糖蛋白A/Protein A–Agarose
• D0064复合蛋白保护剂HPD/Protein protectant HPD
• D0063复合蛋白保护剂DSP50/Protein protectant DSP50
• D0062复合蛋白保护剂DP7/Protein protectant DP7
• D0061复合蛋白保护剂DP4/Protein protectant DP4
• D0060蛋白保护剂AEP-HBC/Protein protectant AEP-HBC