S-腺苷高半胱氨酸水解酶/SAHH

 Description
Biochem/physiol Actions Enzyme in vertebrates which catabolizes S-adenosyl-L-homocysteine.
Unit Definition One unit will hydrolyze 1.0 nanomole of S-adenosyl-L-homocysteine to adenosine and L-homocysteine per min at pH 7.2 at 37 °C.
Physical form Solution in 25 mM Tris, pH 7.4, containing 1 mM dithiothreitol, 1 mM EDTA, and 20% glycerol.

Properties
form buffered aqueous glycerol solution
foreign activity Adenosine deaminase activity ≤1%
shipped in dry ice
storage temp. −70°C

Safety
WGK Germany 3

References
reference Stockand, J.D., et al., S-adenosyl-L-homocysteine hydrolase regulates aldosterone-induced Na+ transport. J. Biol. Chem. 274, 3842-3850, （1999） Abstract
  Robins, M.J., et al., Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5′5′6′6′-tetradehydro-6′-deoxy-6′-halohomoadenosine analogues （4′-haloacetylene analogues derived from adenosine）. J. Med. Chem. 41, 3857-3864, （1998） Abstract

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