肌苷/次黄嘌呤核苷/9-β-D-呋喃核糖基次黄嘌呤/Inosine

 Description
Biochem/physiol Actions Inosine is a potent stimulator of nerve growth factor （NGF） induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage.

Properties
assay ≥99%
mp 222-226 °C （dec.）（lit.）

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 2
RTECS NM7460000

References
reference Chen, P., et al., Inosine induces axonal rewiring and improves behavioral outcome after stroke. Proc. Natl. Acad. Sci. U. S. A. 99, 9031, （2002） Abstract
  Benowitz, L.I. et al., Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury. Proc. Natl. Acad. Sci. U. S. A. 96, 13486, （1999） Abstract
  Braumann, T., et al., Fate of cyclic nucleotides in PC12 cell cultures: uptake, metabolism, and effects of metabolites on nerve growth factor-induced neurite outgrowth. J. Neurochem. 47, 912, （1986） Abstract
Merck Merck 13,4998
Beilstein Beil. 26,IV,2087
  FT-IR 1 （2）, 712:B / FT-IR 2 （3）, 3671:C / FT-NMR 1 （3）, 215:C / IR-Spectra （3）, 1288:E / IR-Spectra （2）, 1121:B / NMR-Reference 2 （2）, 594:A / RegBook 1 （2）, 2469:A / Sax 6, 1615 / Sigma FT-IR 1 （1）, 781:C / Structure Index 1, 390:D:5

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