L-甲状腺素钠/L-Thyroxine sodium salt pentahydrate

Description
Application Literatur s. 89405, L-Thyroxine
Biochem/physiol Actions L-Thyroxine （T4） and triiodo-L-thyronine （T3） are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Properties
assay ≥97.0% （sum of enantiomers, HPLC）
optical activity [α]20/D +16±1°, c = 2% in ethanol/1 M HCl （4:1）
total impurities ~10% water
mp 207-210 （dec.）（lit.）
storage temp. 2-8°C

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
Safety Statements 22-24/25
WGK Germany 3
RTECS YP2833760
 

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