L-高精氨酸盐酸盐/L-Homoarginine hydrochloride

Description
Application The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
Biochem/physiol Actions Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase （TNALP）. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.

Properties
assay ≥98.0% （TLC）
mp 213-215 °C（lit.）
solubility H2O: soluble50 mg/mL, clear to slightly hazy, faintly yellow

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 3
 

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