盐酸土霉素/盐酸地霉素/盐酸氧四环素/Oxytetracycline hydrochloride

 Description
Biochem/physiol Actions Mode of Action: Inhibits protein synthesis （elongation） by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.

Properties
assay ≥95% （HPLC）
form crystalline
color yellow
suitability suitable for 1694 per US EPA

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 2
RTECS QI8225000

References
reference Roberts, M.C., Update on acquired tetracycline resistance genes. FEMS Microbiol. Lett. 245, 195-203, （2005） Abstract
  Aminov, R.I., et al., Detection of tetracycline resistance genes by PCR methods. Methods Mol. Biol., （2004） 268, 3-13 Abstract
  Kroon, A.M., et al., The mitochondrial genetic system as a target for chemotherapy: tetracyclines as cytostatics. Cancer Lett. 25, 33-40, （1984） Abstract
Merck Merck 13,7046
Beilstein Beil. 14,IV,2630

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